silica gel chemically bound with cyanopropyl groups
faster column equilibration than normal silica gel
most polar reversed phase column
YMC-Pack Cyano
Specification
Specification
Particle size / µm
3; 5
5
Pore size / nm
12
30
Surface area / m2g-1
330
100
Carbon content / %
7
2.5
Recommended pH range
2.0 - 7.5
2.0 - 7.5
In reversed phase mode, cyano (nitrile) phases are the most polar and least retentive of all reversed phase packings. Extremely hydrophobic compounds, which do not elute on standard C18 and C8 packings with typical reversed phase eluents, can be separated using cyano phases. Both reversed and normal phase separations can be carried out on this material.