primary amine (-NH2) functionality stable, high coverage monomeric bonded chemistry for applications in aggressive normal phase mode with aqueous eluents for saccharide type compounds, nucleotides and water-soluble vitamins

General

YMC-Pack Amino packings are specifically useful for the analysis of mono- and polysaccharides under aggressive normal phase elution conditions. They can also be used in place of silica for conventional normal phase chromatography using nonpolar solvents.

Properties

YMC-Pack Amino is based on a monomeric bonding of a primary propylamine functionality to YMC’s spherical, ultra pure, high surface area silica with a mean pore diameter of 12 nm. The amine functionality provides retention and allows the separation of polar compounds under aggressive normal phase elution conditions, e.g. the analysis of mono- and polysaccharides using acetonitrile/water eluents. (Since YMC-Gel Amino packings operate under normal phase / HILIC elution conditions, water, which is more polar than acetonitrile, is the stronger solvent.) YMC-Pack Amino can also be used for the separation of isomers of tocopherols and other organic soluble compounds such as paraffins, olefins and aromatics under conventional normal phase conditions.
In aqueous, low pH buffers the amino phase becomes a weak anion exchanger capable of separating negatively charged molecules.

Column care
YMC-Pack Amino is stable towards hydrolysis between pH 2-7,5. Remove acid and buffer salts before storage. For detailed information please refer to the “Column Care and Use Instructions” which are shipped with each analytical column.