Are you looking for the best phase for your separation?
YMC provides you with the new phase selection guide!
The phase selection guide provides a comparison of YMC silica-based C18-phases, including our very latest material, with many popular C18-phases. This powerful tool will help you in choosing the optimum phase for your application!
Our extensive distribution network as well as our highly trained staff at our German headquarters will be happy to help you to find the column that meets your requirements.
For more information or assistance please contact +49 2064 427-0 and ask for Application Support.
Regulatory Support File for YMC-BioPro now available
A further milestone for YMC-BioPro IEX materials has been reached. The Regulatory Support File (RSF) for these high performance IEX resins has been finalized and is now available.
The RSF provides detailed information on product characteristics, quality, stability data, safety data and extractables and so facilitates process development and validation. The document is available for all clients after signing a confidentiality agreement as some of the information is proprietary.
With the Regulatory Support File and the DMF, which has been filed with the FDA beginning of 2010, YMC provides comprehensive regulatory support to our Bioprocess customers. In accordance with YMC’s commitment to deliver more than just very good chromatography media, YMC strives to deliver a complete package of product plus regulatory and scientific support. This ensures that our customers will get all the data needed for process development and validation. Our service is backed by 30 years of experience with clients in biopharmaceutical production.
YMC-BioPro IEX materials feature high dynamic binding capacity at high flow with very competitive pricing. They are available as strong anion and strong cation exchangers with particle sizes of 30 and 75μm, and a pore size of 100 nm. Customized product versions are also available on request.
For more information on the RSF or on YMC-BioPro IEX materials please contact:
Contact:
YMC Europe GmbH
Daniel Kune
Telefon: +49 (0)2064 427-270
Telefax: +49 (0)2064 427-222
E-Mail: kune@ymc.de
printable version:
english
A simple method for the analysis of Nitro-PAH
Polycyclic Aromatic Hydrocarbons (PAH) are compounds of broad interest, as they are ubiquitous in the environment and have been identified partially as carcinogenic, mutagenic and teratogenic. Nitrated Polycyclic Aromatic Hydrocarbons (Nitro-PAH) can be formed from PAH in the environment by reaction with nitrogen oxides (NOx), especially under intensive sunlight. They can be found in particulate matter but also in toners of photocopiers, where they are formed by the reaction of PAH with NOx in the presence of ozone.
Because of the carcinogenic and mutagenic potential of Nitro-PAH, monitoring their presence in the environment is of great importance. For this purpose a simple, isocratic method is presented here, allowing to separate five of the Nitro-PAHs in approximately 4 min.
Column:
Mobile Phase:
Flow rate:
Detection:
Inj.-Vol:
Temp:
YMC PAH, 3 µm, 50 x 4,0 mm ID
acetonitrile / water (55/45)
2,0 ml/min
220 nm
3 µL
25°C